You probably want to mock those global variables instead. The advantage of this is that the globals get reset once you’re done. Python ships with a mocking module that lets you do this.
unittest.mock.patch be used as a decorator:
class TestSomething(self.unittest):
@patch('config.MY_CONFIG_VARIABLE', True)
def test_first_case(self):
self.assertEqual(my_function_with_global_var(), "First result")
You can also use it as a context manager:
def test_first_case(self):
with patch('config.MY_CONFIG_VARIABLE', True):
self.assertEqual(my_function_with_global_var(), "First result")