How to set up a method twice for different parameters with Moq

Moq supports this out of box with argument constraints:

mock.Setup(ms => ms.ValidateUser(
        It.Is<string>(u => u == username), It.Is<string>(p => p == password))
    .Returns(new ValidUserContext { Principal = principal });
mock.Setup(ms => ms.ValidateUser(
        It.Is<string>(u => u != username), It.Is<string>(p => p != password))
    .Returns(new ValidUserContext());

Catch-all It.IsAny also works, but the order is important:

// general constraint first so that it doesn't overwrite more specific ones
mock.Setup(ms => ms.ValidateUser(
        It.IsAny<string>(), It.IsAny<string>())
    .Returns(new ValidUserContext());
mock.Setup(ms => ms.ValidateUser(
        It.Is<string>(u => u == username), It.Is<string>(p => p == password))
    .Returns(new ValidUserContext { Principal = principal });