XML Document SelectSingleNode returns null

The XML document uses the default namespace “http://ratequote.usfnet.usfc.com/v2/x1”. You need to change the SelectSingleNode call to use this namespace.

You need to setup a namspace manager and then supply it to SelectSingleNode.

var nsmgr = new XmlNamespaceManager(doc.NameTable);
nsmgr.AddNamespace("rate", "http://ratequote.usfnet.usfc.com/v2/x1");
var node = xmlDocument.SelectSingleNode("//rate:RateQuote", nsmgr);

EDIT
The RateQuoteResponse element has a default namespace xmlns="...". This means that all elements use this namespace also, unless specifically overridden.