IPython comes with some automatic reloading magic:

%load_ext autoreload
%autoreload 2

It will reload all changed modules every time before executing a new line. The way this works is slightly different than dreload. Some caveats apply, type %autoreload? to see what can go wrong.

If you want to always enable this settings, modify your IPython configuration file ~/.ipython/profile_default/ipython_config.py[1] and appending:

c.InteractiveShellApp.extensions = ['autoreload']     
c.InteractiveShellApp.exec_lines = ['%autoreload 2']

Credit to @Kos via a comment below.

If you don’t have the file ~/.ipython/profile_default/ipython_config.py, you need to call ipython profile create first. Or the file may be located at $IPYTHONDIR.