You can use pandas’ ExcelFile parse method to read Excel sheets, see io docs:
xls = pd.ExcelFile('C:\Users\cb\Machine_Learning\cMap_Joins.xlsm')
df = xls.parse('Sheet1', skiprows=4, index_col=None, na_values=['NA'])
skiprows will ignore the first 4 rows (i.e. start at row index 4), and several other options.