List Highest Correlation Pairs from a Large Correlation Matrix in Pandas?

You can use DataFrame.values to get an numpy array of the data and then use NumPy functions such as argsort() to get the most correlated pairs.

But if you want to do this in pandas, you can unstack and sort the DataFrame:

import pandas as pd
import numpy as np

shape = (50, 4460)

data = np.random.normal(size=shape)

data[:, 1000] += data[:, 2000]

df = pd.DataFrame(data)

c = df.corr().abs()

s = c.unstack()
so = s.sort_values(kind="quicksort")

print so[-4470:-4460]

Here is the output:

2192  1522    0.636198
1522  2192    0.636198
3677  2027    0.641817
2027  3677    0.641817
242   130     0.646760
130   242     0.646760
1171  2733    0.670048
2733  1171    0.670048
1000  2000    0.742340
2000  1000    0.742340
dtype: float64