Is it possible to split a sequence of pandas commands across multiple lines?

In python you can continue to the next line by ending your line with a reverse slash or by enclosing the expression in parenthesis.

df.groupby[['x','y']] \
.apply(lambda x: (np.max(x['z'])-np.min(x['z']))) \
.sort_values(ascending=False)

or

(df.groupby[['x','y']]
.apply(lambda x: (np.max(x['z'])-np.min(x['z'])))
.sort_values(ascending=False))