How to exit the entire application from a Python thread?

Short answer: use os._exit.

Long answer with example:

I yanked and slightly modified a simple threading example from a tutorial on DevShed:

import threading, sys, os

theVar = 1

class MyThread ( threading.Thread ):

   def run ( self ):

      global theVar
      print 'This is thread ' + str ( theVar ) + ' speaking.'
      print 'Hello and good bye.'
      theVar = theVar + 1
      if theVar == 4:
          #sys.exit(1)
          os._exit(1)
      print '(done)'

for x in xrange ( 7 ):
   MyThread().start()

If you keep sys.exit(1) commented out, the script will die after the third thread prints out. If you use sys.exit(1) and comment out os._exit(1), the third thread does not print (done), and the program runs through all seven threads.

os._exit “should normally only be used in the child process after a fork()” — and a separate thread is close enough to that for your purpose. Also note that there are several enumerated values listed right after os._exit in that manual page, and you should prefer those as arguments to os._exit instead of simple numbers like I used in the example above.