Well, I’d like to best Triptych’s solution with … a one-liner!
>>> def clean(varStr): return re.sub('\W|^(?=\d)','_', varStr)
...
>>> clean('32v2 g #Gmw845h$W b53wi ')
'_32v2_g__Gmw845h_W_b53wi_'
This substitution replaces any non-variable appropriate character with underscore and inserts underscore in front if the string starts with a digit. IMO, ‘name/with/slashes’ looks better as variable name name_with_slashes than as namewithslashes.