Exclusive access could not be obtained because the database is in use

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A restore can only happen if the database does not have any connections to it (besides yours). The easy way on a MS SQL Server to kick all users off is:

ALTER DATABASE [MyDB] SET Single_User WITH Rollback Immediate
GO

Now, you can perform your restore with impunity. Make sure you set it back to Multi-user mode when you’re done with the restore:

ALTER DATABASE [MyDB] SET Multi_User
GO

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