Dropping Multiple Columns from a dataframe

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To delete multiple columns at the same time in pandas, you could specify the column names as shown below. The option inplace=True is needed if one wants the change affected column in the same dataframe. Otherwise remove it.

flight_data_copy.drop(['TailNum', 'OriginStateFips', 
                'DestStateFips', 'Diverted'], axis=1, inplace=True)

Source: Python Pandas – Deleting multiple series from a data frame in one command

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