Disable generating PDB files in MsBuild

You may have PDB generation in your release configuration. Add this to your release settings:

<DebugSymbols>false</DebugSymbols>
<DebugType>None</DebugType>

You can also, do this in your project configuration inside visual studio. Disable PDB Generation

Also, if running MSBuild from the command line, the command line arguments would be

MSBuild.exe YourProject.csproj /p:DebugSymbols=false /p:DebugType=None