d={
'key1': [10, 100.1, 0.98, 1.2],
'key2': [72.5],
'key3': [1, 5.2, 71.2, 9, 10.11, 12.21, 65, 7]
}
df=pd.DataFrame.from_dict(d,orient="index").transpose()
Then df is
key3 key2 key1
0 1.00 72.5 10.00
1 5.20 NaN 100.10
2 71.20 NaN 0.98
3 9.00 NaN 1.20
4 10.11 NaN NaN
Note that numpy has some built in functions that can do calculations ignoring NaN values, which may be relevant here. For example, if you want to find the mean of 'key1' column, you can do it as follows:
import numpy as np
np.nanmean(df[['key1']])
28.07
Other useful functions include numpy.nanstd, numpy.nanvar, numpy.nanmedian, numpy.nansum.
EDIT: Note that the functions from your basic functions link can also handle nan values. However, their estimators may be different from those of numpy. For example, they calculate the unbiased estimator of sample variance, while the numpy version calculates the “usual” estimator of sample variance.