You can create a patch file by restricting the output of git diff by listing paths at the end of the command (after a -- to avoid any potential clashes between path names and branch names).
For example, you could do the following:
git diff origin/master HEAD -- app/models/region.rb doc/ > changes.patch
Above commands generate a patch that shows only the differences for a particular file: region.rb and a particular directory : doc when compared to origin/master
Then you can apply the patch using
patch -p1 < changes.patch
The -p1 tells patch to strip the a/ and b/ in the paths in the patch