Yes, the default macOS base64 implementation doesn’t have the -w flag. What does that flag do?
-w, --wrap=COLSWrap encoded lines after COLS character (default 76). Use 0 to disable line wrapping.
And here’s the macOS man page for base64:
-b count --break=countInsert line breaks every count characters. Default is 0, which generates an unbroken stream.
So, the flag is called -b in macOS, and it already defaults to 0, which means base64 in macOS has the same behaviour as base64 -w0 on Linux. You’ll have to detect which platform you run on to use the appropriate variation of the command. See here: Detect the OS from a Bash script; the platform name you’re looking for for macOS is “Darwin”.