PyQt Widget connect() and disconnect()

If you need to reconnect signals in many places, then you could define a generic utility function like this:

def reconnect(signal, newhandler=None, oldhandler=None):        
    try:
        if oldhandler is not None:
            while True:
                signal.disconnect(oldhandler)
        else:
            signal.disconnect()
    except TypeError:
        pass
    if newhandler is not None:
        signal.connect(newhandler)

...

if connected:
    reconnect(myButton.clicked, function_A)
else:
    reconnect(myButton.clicked, function_B)

(NB: the loop is needed for safely disconnecting a specific handler, because it may have been connected multple times, and disconnect(slot) only removes one connection at a time.).