I had the same issue and finally figured it out. This is for a vertical ScrollView.
Put your ScrollView inside a RelativeLayout and center it in the RelativeLayout. In order for this to work, your ScrollView should have
android:layout_height="wrap_content"
This is how the final code should look like:
<?xml version="1.0" encoding="utf-8"?>
<RelativeLayout xmlns:android="http://schemas.android.com/apk/res/android"
android:layout_width="fill_parent"
android:layout_height="fill_parent">
<ScrollView
android:id="@+id/scrollView1"
android:layout_width="fill_parent"
android:layout_height="wrap_content"
android:layout_centerVertical="true" >
<LinearLayout
android:id="@+id/linearLayout1"
android:layout_width="match_parent"
android:layout_height="wrap_content"
android:orientation="vertical">
<Button
android:id="@+id/button1"
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:text="b1"/>
<Button
android:id="@+id/button2"
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:text="b2"/>
<Button
android:id="@+id/button3"
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:text="b3"/>
</LinearLayout>
</ScrollView>
</RelativeLayout>