You guys are all trying to answer the question from a programmer’s perspective. I think the original poster was looking for an alternative which is more graphic-friendly – one that would offer a different concept.
Even if CSS3 gets adopted cross browser, I believe that the CSS way of laying out stuff (inline box, floats, margins, etc) is awful. I am a programmer, but my father is a graphic designer, and I am pretty sure that the layout software they were using 20 years was in some aspects easier and more advanced than CSS.