This really works, I spent a lot of time trying multiple variants.
import smtplib
from email.mime.text import MIMEText
s = smtplib.SMTP('smtp.uk.xensource.com')
s.set_debuglevel(1)
msg = MIMEText("""body""")
sender="me@example.com"
recipients = ['john.doe@example.com', 'john.smith@example.co.uk']
msg['Subject'] = "subject line"
msg['From'] = sender
msg['To'] = ", ".join(recipients)
s.sendmail(sender, recipients, msg.as_string())