How to redraw DataTable with new data

You have to first clear the table and then add new data using row.add() function. At last step adjust also column size so that table renders correctly.

$('#upload-new-data').on('click', function () {
   datatable.clear().draw();
   datatable.rows.add(NewlyCreatedData); // Add new data
   datatable.columns.adjust().draw(); // Redraw the DataTable
});

Also if you want to find a mapping between old and new datatable API functions bookmark this