Simple add a ^ to beginning and a $ to the end
^ tells tells the regex to match the beginning of the url
$ tells tells the regex to match the end of the url
redirectMatch 301 ^/user$ http://clients.mydomain.com
So now your rule will only match /user and not /some/user or /user/name or /some/user/name
NOTE: If you want to match /user/ and /user then use ^/user/?$
? says to match the previous character/group zero to one times