How to pass multiple parameter to @Directives (@Components) in Angular with TypeScript?

From the Documentation

As with components, you can add as many directive property bindings as
you need by stringing them along in the template.

Add an input property to HighlightDirective called defaultColor:

@Input() defaultColor: string;

Markup

<p [myHighlight]="color" defaultColor="violet">
  Highlight me too!
</p>

Angular knows that the defaultColor binding belongs to the HighlightDirective because you made it public with the @Input
decorator.

Either way, the @Input decorator tells Angular that this property is
public and available for binding by a parent component. Without
@Input, Angular refuses to bind to the property.

For your example

With many parameters

Add properties into the Directive class with @Input() decorator

@Directive({
    selector: '[selectable]'
})
export class SelectableDirective{
    private el: HTMLElement;

    @Input('selectable') option:any;   
    @Input('first') f;
    @Input('second') s;

    ...
}

And in the template pass bound properties to your li element

<li *ngFor="let opt of currentQuestion.options" 
    [selectable] = 'opt' 
    [first]='YourParameterHere'
    [second]='YourParameterHere'
    (selectedOption) = 'onOptionSelection($event)'>
    {{opt.option}}
</li>

Here on the li element we have a directive with name selectable. In the selectable we have two @Input()‘s, f with name first and s with name second. We have applied these two on the li properties with name [first] and [second]. And our directive will find these properties on that li element, which are set for him with @Input() decorator. So selectable, [first] and [second] will be bound to every directive on li, which has property with these names.

With single parameter

@Directive({
    selector: '[selectable]'
})
export class SelectableDirective{
    private el: HTMLElement;

    @Input('selectable') option:any;   
    @Input('params') params;

    ...
}

Markup

<li *ngFor="let opt of currentQuestion.options" 
    [selectable] = 'opt' 
    [params]='{firstParam: 1, seconParam: 2, thirdParam: 3}'
    (selectedOption) = 'onOptionSelection($event)'>
    {{opt.option}}
</li>