How to delete multiple topics in Apache Kafka

Yes you can use regex-like expressions when deleting topics with the kafka-topics.sh tool:

For example, to delete all topics starting with giorgos-:

./bin/kafka-topics.sh --zookeeper localhost:2181 --delete --topic 'giorgos-.*'

Using the Admin APIs, you can also delete several topics at once, see
AdminClient.deleteTopics