A computer is like an onion, it has many many layers, from the inner core of pure hardware to the outermost application layer. Each layer exposes parts of itself to the next outer layer, so that the outer layer may use some of the inner layers functionality.
In the case of e.g. Windows the operating system exposes the so-called WIN32 API for applications running on Windows. The Qt library uses that API to provide applications using Qt to its own API. You use Qt, Qt uses WIN32, WIN32 uses lower levels of the Windows operating system, and so on until it’s electrical signals in the hardware.