How can I get/set a struct member by offset

The approach you’ve outlined is roughly correct, although you should use offsetof instead of attempting to figure out the offset on your own. I’m not sure why you mention memset — it sets the contents of a block to a specified value, which seems quite unrelated to the question at hand.

Here’s some code to demonstrate how it works:

#include <stdio.h>
#include <stdlib.h>
#include <stddef.h>

typedef struct x {
    int member_a;
    int member_b;
} x;

int main() { 
    x *s = malloc(sizeof(x));
    char *base;
    size_t offset;
    int *b;

    // initialize both members to known values
    s->member_a = 1;
    s->member_b = 2;

    // get base address
    base = (char *)s;

    // and the offset to member_b
    offset = offsetof(x, member_b);

    // Compute address of member_b
    b = (int *)(base+offset);

    // write to member_b via our pointer
    *b = 10;

    // print out via name, to show it was changed to new value.
    printf("%d\n", s->member_b);
    return 0;
}