Get first element of Series without knowing the index [duplicate]

Use iloc to access by position (rather than label):

In [11]: df = pd.DataFrame([[1, 2], [3, 4]], ['a', 'b'], ['A', 'B'])

In [12]: df
Out[12]: 
   A  B
a  1  2
b  3  4

In [13]: df.iloc[0]  # first row in a DataFrame
Out[13]: 
A    1
B    2
Name: a, dtype: int64

In [14]: df['A'].iloc[0]  # first item in a Series (Column)
Out[14]: 1