No, it is not OK to use a blocking API call in a node server as you describe. Your site’s responsiveness to many concurrent connections will take a huge hit. It’s also just blatantly violating the #1 principle of node.
The key to node working is that while it is waiting on IO, it is doing CPU/memory processing at the same time. This requires asynchronous calls exclusively. So if you have 100 clients reading 100 JSON files, node can ask the OS to read those 100 files but while waiting for the OS to return the file data when it is available, node can be processing other aspects of those 100 network requests. If you have a single synchronous call, ALL of your client processing stops entirely while that operation completes. So client number 100’s connection waits with no processing whatsoever while you read files for clients 1, 2, 3, 4, and so on sequentially. This is Failville.
Here’s another analogy. If you went to a restaurant and were the only customer, you would probably get faster service if a single person sat you, took your order, cooked it, served it to you, and handled the bill without the coordination overhead of dealing with the host/hostess, server, head chef, line cooks, cashiers, etc. However, with 100 customers in the restaurant, the extra coordination means things happen in parallel and the overall responsiveness of the restaurant is increased way beyond what it would be if a single person were trying to handle 100 customers on their own.