You can have a React component make an ajax request to your server, when the application loads, to fetch “interface version”. In the server API, you can maintain an incremental value for the client version. The React component can store this value on the client (cookie/local storage/etc). When it detects a change, it can invoke window.location.reload(true); which should force the browser to discard client cache and reload the SPA. Or better still, inform the end-user that a new version will be loaded and ask them if they wish to save the work and then reload etc. Depends on what you wanna do.