How to convert tuple of tuples to pandas.DataFrame in Python?

import pandas as pd

s = ((1,0,0,0,),(2,3,0,0,),(4,5,6,0,),(7,8,9,10,))

print pd.DataFrame(list(s))

#    0  1  2   3
# 0  1  0  0   0
# 1  2  3  0   0
# 2  4  5  6   0
# 3  7  8  9  10

print pd.DataFrame(list(s), columns=[1,2,3,4], index=[1,2,3,4])  

#    1  2  3   4
# 1  1  0  0   0
# 2  2  3  0   0
# 3  4  5  6   0
# 4  7  8  9  10