For an unauthenticated proxy (and assuming it’s the Ethernet service you want to configure):
networksetup -setwebproxy Ethernet proxy.example.net 80 off
for authenticated:
networksetup -setwebproxy Ethernet proxy.example.net 80 on proxyuser "p4ssw0rd"
and to turn it off:
networksetup -setwebproxystate Ethernet off
If the network service isn’t named just “Ethernet”, you may need to parse networksetup -listallnetworkservices
or -listnetworkserviceorder
to get the correct name.