SQLiteDatabase
SQLiteDatabase has methods to create, delete, execute SQL commands,
and perform other common database management tasks.
SQLiteOpenHelper
A helper class to manage database creation and version management.
I will say this much, the onUpgrade that comes with SQLiteOpenHelper comes in REALLY handy when upgrading your application. It’s mainly for creation and upgrading / version management. SQLiteDatabase is mainly for CRUD operations (you can create with it but that is what SQLiteOpenHelper is for).