Yes, you just have to use variable interpolation. Example:
@mixin post-link ($class, $color, $hover) {
a.#{$class}:link {
color: $color;
}
a.#{$class}:hover {
color: $hover;
}
}
Example on SassMeister: http://sassmeister.com/gist/9533103
The key is adding #{
and }
around your variable names to get them expanded.