Simple:
my_str = "abcdefghij"
my_str = my_str[:-1]
Try the following code snippet to better understand how it works by casting the string as a list:
str1 = "abcdefghij"
list1 = list(str1)
print(list1)
list2 = list1[:-1]
print(list2)
In case, you want to accept the string from the user:
str1 = input("Enter :")
list1 = list(str1)
print(list1)
list2 = list1[:-1]
print(list2)
To make it take away the last word from a sentence (with words separated by whitespace like space):
str1 = input("Enter :")
list1 = str1.split()
print(list1)
list2 = list1[:-1]
print(list2)