How can I join two tables but only return rows that don’t match?

SELECT T1.*
    FROM T1
    WHERE NOT EXISTS(SELECT NULL
                         FROM T2
                         WHERE T1.ID = T2.ID 
                             AND T1.Date = T2.Date
                             AND T1.Hour = T2.Hour)

It could also be done with a LEFT JOIN:

SELECT T1.*
    FROM T1
        LEFT JOIN T2
            ON T1.ID = T2.ID
                AND T1.Date = T2.Date
                AND T1.Hour = T2.Hour
    WHERE T2.ID IS NULL