Here are a few thoughts… I have only used Numpy, Scipy, and Matplotlib for financial calculations.
- py-fi – very basic financial functions
- fin2py – financial tools
- Numpy/Scipy – covers all of the statistics basics
- Matplotlib – plotting financial functions
- RPy – a Python interface to R allowing use of R libraries
- ystockquote – Python API for Yahoo! Stock Data
- QuantLib – Open source library (supposedly has Python Bindings)
- PyFinancial – Docs in Spanish
- PyMacLab – “Series of classes useful for conducting research in dynamic macroeconomics”
- TSDB – for storing large volumes of time series data
- PyVol – volatility estimation of financial time series