You can get a plugin (and an explanation about what things are detected as changes) in this post: http://alfonsoml.blogspot.com/2011/03/onchange-event-for-ckeditor.html so you can do things like
for (var i in CKEDITOR.instances) {
CKEDITOR.instances[i].on('change', function() {alert('test 1 2 3')});
}