Genymotion by default uses its own ADB binary. If it has a different version than the one Android Studio is using, they can conflict and you get lots of issues. One of them can be Genymotion not being detected, and problems deploying apps.
I would recommend setting Genymotion to use the ADB/Android SDK that Android Studio is also using, instead of using the default one. That way you will avoid conflicts on future updates.
