Just created and tested it. Looks like you want.
<?xml version="1.0" encoding="utf-8"?>
<RelativeLayout xmlns:android="http://schemas.android.com/apk/res/android"
android:layout_width="match_parent"
android:layout_height="match_parent">
<LinearLayout
android:id="@+id/buttons"
android:layout_width="match_parent"
android:layout_height="wrap_content"
android:orientation="horizontal"
android:gravity="center"
android:layout_alignParentBottom="true">
<Button
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:text="Custom Button1"/>
<Button
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:text="Custom Button2"/>
</LinearLayout>
<ScrollView
android:layout_width="match_parent"
android:layout_height="match_parent"
android:layout_above="@id/buttons">
<!--Scrollable content here-->
<LinearLayout
android:layout_width="match_parent"
android:layout_height="wrap_content"
android:orientation="vertical">
<TextView
android:layout_height="wrap_content"
android:layout_width="wrap_content"
android:text="test text"
android:textSize="40dp"/>
</LinearLayout>
</ScrollView>
</RelativeLayout>