None of the existing answers accomplish what the OP originally asked for, which is to override the default Reason-Phrase (the text appearing immediately after the status code) sent by Express.
What you want is res.statusMessage. This is not part of Express, it’s a property of the underlying http.Response object in Node.js 0.11+.
You can use it like this (tested in Express 4.x):
function(req, res) {
res.statusMessage = "Current password does not match";
res.status(400).end();
}
Then use curl to verify that it works:
$ curl -i -s http://localhost:3100/
HTTP/1.1 400 Current password does not match
X-Powered-By: Express
Date: Fri, 08 Apr 2016 19:04:35 GMT
Connection: keep-alive
Content-Length: 0