No, sqlite3 databases are very lightweight systems. They need no server and all data is stored in one file. A username/password is not supported by the sqlite/sqlite3 package.
In order to achieve simplicity, SQLite has had to sacrifice other characteristics that some people find useful, such as high concurrency, fine-grained access control, a rich set of built-in functions, stored procedures, esoteric SQL language features, XML and/or Java extensions, tera- or peta-byte scalability, and so forth.
(sqlite, when to use)
However, since it’s only a file you can encrypt the file with a password to protect your data.