How to remove empty lines with or without whitespace

Try list comprehension and string.strip():

>>> mystr = "L1\nL2\n\nL3\nL4\n  \n\nL5"
>>> mystr.split('\n')
['L1', 'L2', '', 'L3', 'L4', '  ', '', 'L5']
>>> [line for line in mystr.split('\n') if line.strip()]
['L1', 'L2', 'L3', 'L4', 'L5']