I believe you should follow the approach outlined here: https://uwsgi-docs.readthedocs.io/en/latest/WSGIquickstart.html#bonus-multiple-python-versions-for-the-same-uwsgi-binary
Basically:
- Build a core uwsgi binary that does not have the Python plugin (to be used by the emperor):
make PROFILE=nolang - And then build plugins for each python version that you use (for the vassals), and configure each vassal to use the correct plugin.