Don’t use <div> tags to make clickable elements. Use <a> or <button> elements. This enables browsers with JavaScript disabled to interact with them as expected. Even if your functionality requires JavaScript and there is no reasonable default behaviour you can assign to an <a>, use it regardless – it conveys “clickable” semantics.
In general, choose the tag that most closely describes the function of its content, not the appearance of its content, and avoid unnecessary <div> tags lest your documents suffer from divitis.